Acetone → HCID 86594881、化合物

HRID 1354758

反応式

HRID 1354758 の反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:12][CH2:11][C@H:10]([CH2:13][NH:14][C:15](=[O:21])[O:16][C:17]([CH3:20])([CH3:19])[CH3:18])[CH2:9]2)=[C:4]([F:22])[CH:3]=1.C(O[BH-](OC(=O)C)OC(=O)C)(=O)C.[CH3:36][C:37]([CH3:39])=O>>[F:22][C:4]1[CH:3]=[C:2]([NH:1][CH:37]([CH3:39])[CH3:36])[CH:7]=[CH:6][C:5]=1[N:8]1[CH2:12][CH2:11][C@H:10]([CH2:13][NH:14][C:15](=[O:21])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:9]1

参加物

4

反応物 3

HCID 180AcetoneHCID 2724942TriacetoxyborohydrideHCID 68988249tert-Butyl (R)-[1-(4-amino-2-fluorophenyl)pyrrolidin-3-yl]methylcarbamate

生成物 1

HCID 86594881HCID 86594881、化合物

実験手順

tert-Butyl (R)-[1-(4-amino-2-fluorophenyl)pyrrolidin-3-yl]methylcarbamate was alkylated with acetone using triacetoxyborohydride as reducing agent by method N. This resulted in the product with the molecular weight of 351.47 (C19H30FN3O2); MS (ESI): 352 (M+H+).

後処理

  1. customThis resulted in the product with the molecular weight of 351.47 (C19H30FN3O2)

出典と根拠

ORDレコード
ord-2cd95b45e15e4e1387e3f728178a8533
出典データセット
uspto-grants-2007_05
特許番号
US07223788B2

関連ノート

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