Carbonic acid-guanidine (1:1) → 1-{1-[4-(2,4-diamino-6-phenylpyrido[2,3-d]pyrimidin-7-yl)benzyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one

反応式

C(=O)(O)O.[NH2:5][C:6]([NH2:8])=[NH:7].CC(C)([O-])C.[K+].Cl[C:16]1[N:23]=[C:22]([C:24]2[CH:29]=[CH:28][C:27]([CH2:30][N:31]3[CH2:36][CH2:35][CH:34]([N:37]4[C:41]5[CH:42]=[CH:43][CH:44]=[CH:45][C:40]=5[NH:39][C:38]4=[O:46])[CH2:33][CH2:32]3)=[CH:26][CH:25]=2)[C:21]([C:47]2[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=2)=[CH:20][C:17]=1[C:18]#[N:19]>CC(N(C)C)=O>[NH2:7][C:6]1[N:8]=[C:18]([NH2:19])[C:17]2[CH:20]=[C:21]([C:47]3[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=3)[C:22]([C:24]3[CH:29]=[CH:28][C:27]([CH2:30][N:31]4[CH2:36][CH2:35][CH:34]([N:37]5[C:41]6[CH:42]=[CH:43][CH:44]=[CH:45][C:40]=6[NH:39][C:38]5=[O:46])[CH2:33][CH2:32]4)=[CH:26][CH:25]=3)=[N:23][C:16]=2[N:5]=1