Dimethylamine → HCID 18506777、化合物

反応式

CS[C:3]1[N:4]=[N:5][C:6]([C:20]#[N:21])=[C:7]([N:9]2[CH2:15][CH2:14][C:13]3[CH:16]=[CH:17][CH:18]=[CH:19][C:12]=3[CH2:11][CH2:10]2)[N:8]=1.[CH3:22][NH:23][CH3:24]>>[CH3:22][N:23]([CH3:24])[C:3]1[N:4]=[N:5][C:6]([C:20]#[N:21])=[C:7]([N:9]2[CH2:15][CH2:14][C:13]3[CH:16]=[CH:17][CH:18]=[CH:19][C:12]=3[CH2:11][CH2:10]2)[N:8]=1

参加物

反応物 2

HCID 674Dimethylamine

HCID 18506776HCID 18506776、化合物

生成物 1

HCID 18506777HCID 18506777、化合物

実験手順

In an analogous manner as described in example 2, reaction of 3-methylsulfanyl-5-(1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-[1,2,4]triazine-6-carbonitrile with dimethylamine (33% solution in absolute ethanol) in a sealed tube at 110° C. yielded 3-dimethylamino-5-(1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-[1,2,4]triazine-6-carbonitrile as a light brown amorphous solid; MS: 295 (M+H)+.

出典と根拠

ORDレコード: ord-b9fe06fc85494d3093b9133004132c47
出典データセット: uspto-grants-2003_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06586422B2

反応ノート

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