化工社化工社 化学情報印刷レポート · 研究参考用
1,8-Diazabicyclo(5.4.0)undec-7-ene → 2-Amino-4-[(3,5-dimethyl-pyridin-2-yl-methyl)-amino]-6-pyrazol-1-yl-pyrimidine-5-carbonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| 反応物 | (3,5-Dimethylpyridin-2-yl)methanamine dihydrochloride | HCID 18507411 | — |
| 反応物 | 2-Amino-4-methanesulfinyl-6-pyrazol-1-yl-pyrimidine-5-carbonitrile | HCID 18507520 | — |
| 溶媒 | 1,2-Dimethoxyethane | HCID 8071 | — |
| 生成物 | 2-Amino-4-[(3,5-dimethyl-pyridin-2-yl-methyl)-amino]-6-pyrazol-1-yl-pyrimidine-5-carbonitrile | HCID 18507501 | — |
反応手順
From 2-amino-4-methanesulfinyl-6-pyrazol-1-yl-pyrimidine-5-carbonitrile, C-(3,5-dimethyl-pyridin-2-yl)-methylamine dihydrochloride and DBU in DME. ES-MS m/e (%): 321 (M+H+, 100).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06586441B2 |
| 出典データセット | uspto-grants-2003_07 |
| ORD ID | ord-6ee6ddcee50e4ac095f3a4039ff9f79b |
| 出典メモ | uspto-grants-2003_07 |