HCID 18508367、化合物 → HCID 9930663、化合物
反応式
[C:1]1([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH:6]=[CH:5][C:4]([CH2:7][O:8][C:9]2[CH:14]=[CH:13][C:12]([CH2:15][C:16]([NH:18][CH2:19][CH2:20][NH:21]C(=O)OC(C)(C)C)=[O:17])=[CH:11][CH:10]=2)=[CH:3][CH:2]=1.[ClH:35].C(OCC)(=O)C>C(O)(=O)C>[ClH:35].[NH2:21][CH2:20][CH2:19][NH:18][C:16](=[O:17])[CH2:15][C:12]1[CH:13]=[CH:14][C:9]([O:8][CH2:7][C:4]2[CH:3]=[CH:2][C:1]([C:29]3[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=3)=[CH:6][CH:5]=2)=[CH:10][CH:11]=1参加物
4
実験手順
To a solution of tert-butyl 2-(((4-([1,1′-biphenyl]-4-ylmethoxy)phenyl)acetyl)amino)ethylcarbamate (1.5 g) in acetic acid (100 ml) was added 4N hydrochloric acid/ethyl acetate (4 ml) at room temperature. After stirring at room temperature for 2 hr, the precipitate was collected by filtration, which was washed with ethyl ether and dried to obtain the titled compound (0.9 g).
後処理
- filtration