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Methanol → methyl (2S)-4-methyl-2-(methylamino)pentanoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | 1,4-Dioxane | HCID 31275 | — |
| 反応物 | N-Methylleucine | HCID 2777993 | — |
| 溶媒 | Hydrochloric Acid | HCID 313 | — |
| 生成物 | methyl (2S)-4-methyl-2-(methylamino)pentanoate | HCID 10921446 | 100% |
反応手順
N-methyl-L-leucine (1.3 g, 8.95 mmol) was dissolved in 4M HCl, 1,4 dioxane (10 mL) and methanol (10 mL). The solution was stirred overnight at room temperature, then concentrated to afford the title compound as a white solid (100%). MS (ESI): 160.0 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06586466B2 |
| 出典データセット | uspto-grants-2003_07 |
| ORD ID | ord-c84cddade0974f8e87532868bc68310d |
| 出典メモ | uspto-grants-2003_07 |