Acetyl chloride → Acetamide, N-ethyl-N-(4-nitrophenyl)-
反応式
[CH2:1]([NH:3][C:4]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][CH:5]=1)[CH3:2].[C:13](Cl)(=[O:15])[CH3:14]>C1C=CC=CC=1>[C:13]([N:3]([CH2:1][CH3:2])[C:4]1[CH:5]=[CH:6][C:7]([N+:10]([O-:12])=[O:11])=[CH:8][CH:9]=1)(=[O:15])[CH3:14]参加物
4
実験手順
To a suspension of N-ethyl 4-nitroaniline (1.5 g, 9.026 mmol) in benzene (15 ml), is added acetylchloride (10 ml) and the mixture refluxed for 40 minutes. The solvent is removed by evaporation. The residue is dissolved in ethyl acetate prior to washing with 2N sodium bicarbonate and water, drying (MgSO4) and evaporation. The product is dried under vacuum; ES+ (M+1) 208.57.
後処理
- temperaturethe mixture refluxed for 40 minutes
- customThe solvent is removed by evaporation
- dissolutionThe residue is dissolved in ethyl acetate
- washto washing with 2N sodium bicarbonate and water
- customdrying
- custom(MgSO4) and evaporation
- customThe product is dried under vacuum
出典と根拠
- ORDレコード
- ord-a467fa6e925242a88b7ed78699b8dc79
- 出典データセット
- uspto-grants-2003_07
- 特許番号
- US06589950B1
反応ノート
読み込み中…