Sulfuric Acid → HCID 18506076、化合物

反応式

[NH2:1][C:2]1[CH:18]=[CH:17][CH:16]=[CH:15][C:3]=1[O:4][C:5]1[CH:6]=[C:7](C#N)[C:8](=[CH:11][CH:12]=1)[C:9]#[N:10].S(=O)(=O)(O)[OH:20].[C:24](=[O:27])([O-])O.[Na+]>O>[NH2:1][C:2]1[CH:18]=[CH:17][CH:16]=[CH:15][C:3]=1[O:4][C:5]1[CH:6]=[C:7]2[C:8](=[CH:11][CH:12]=1)[C:9](=[O:20])[NH:10][C:24]2=[O:27]

参加物

実験手順

4-(2-Aminophenoxy)phthalonitrile (1.55 g, 6.6 mmol) was stirred with conc. sulphuric acid (9 ml) at room temperature for 15 hours. The mixture was purred into crushed ice and the pH was adjusted to 10 with diluted sodium hydrogencarbonate in water. The mixture was left for the weekend at room temperature. The resulting precipitate was filtered off and washed twice with water (2×50 ml). The crystals were dried to give yellow crystals of 5-(2-aminophenoxy)isoindole-1,3dione) (yield: 1.41 g (84%)). Mp: 211.6-211.9° C.