化工社化工社 化学情報印刷レポート · 研究参考用
4-Methyl-3-nitrobenzyl alcohol → (3-Amino-4-methylphenyl)methanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Methyl-3-nitrobenzyl alcohol | HCID 123497 | — |
| 反応物 | HCID 178418361 | HCID 178418361 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | (3-Amino-4-methylphenyl)methanol | HCID 586243 | 94.8% |
反応手順
4-Methyl-3-nitro benzylalcohol (9.7 g, 58 mmol) in ethanol (200 mL) was reduced under 4 atmospheres of hydrogen gas for 4 hours in the presence of 10% Pd/C (0.5 g) to yield after a standard workup 7.54 g (93%) of the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06593335B1 |
| 出典データセット | uspto-grants-2003_07 |
| ORD ID | ord-83dda6c0962d4d169663d0f091c17d1b |
| 出典メモ | uspto-grants-2003_07 |