化工社化工社 化学情報印刷レポート · 研究参考用
3-Methyl-2-nitroanisole → 2-Methoxy-6-methylaniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Methyl-2-nitroanisole | HCID 79291 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 2-Methoxy-6-methylaniline | HCID 459249 | — |
反応手順
A solution of 1-methoxy-3-methyl-2-nitrobenzene (15.04 g, 0.09 mol) in ethanol (250 ml) was hydrogenated over 10% palladium on charcoal (4 g) at atmospheric pressure and at room temperature, for 18 h. The catalyst was removed by filtration, and the filtrate evaporated under reduced pressure to leave the title compound (D28) as an amber oil, which crystallised on standing (11.18 g, 91%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06599904B2 |
| 出典データセット | uspto-grants-2003_07 |
| ORD ID | ord-6d7e7e529731450082821b906b6e9160 |
| 出典メモ | uspto-grants-2003_07 |