Methanol → HCID 18182209、化合物
反応式
Cl[C:2]1[C:7]([C:8]([C:10]2[S:11][CH:12]=[CH:13][CH:14]=2)=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1.[CH3:15][OH:16].C[O-].[Na+]>O>[CH3:15][O:16][C:2]1[C:7]([C:8]([C:10]2[S:11][CH:12]=[CH:13][CH:14]=2)=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1参加物
5
実験手順
A mixture of 1.64 g of 2-chloro-3-(2-thienylcarbonyl)pyridine, 4.5 ml of a methanol solution of 28% sodium methoxide and 2.0 ml of methanol was heated under stirring for 30 minutes. After cooling as it was, water was added to the reaction solution and the mixture was extracted with ethyl acetate. The organic phase was washed with brine and the solvent was removed, to give 1.46 g of the target compound.
後処理
- temperaturewas heated
- temperatureAfter cooling as it
- extractionthe mixture was extracted with ethyl acetate
- washThe organic phase was washed with brine
- customthe solvent was removed
出典と根拠
- ORDレコード
- ord-af2b9092f05f4d2892503c49254bcc4f
- 出典データセット
- uspto-grants-2003_07
- 特許番号
- US06599917B1
反応ノート
読み込み中…