Ethyl 2-hydroxy-5-(4-methoxyphenyl)pentanoate → Ethyl (2R)-2-hydroxy-5-(4-methoxyphenyl)pentanoate
反応式
O[C@H](CCCC1C=CC(OC)=CC=1)C(O)=O.[OH:17][CH:18]([CH2:24][CH2:25][CH2:26][C:27]1[CH:32]=[CH:31][C:30]([O:33][CH3:34])=[CH:29][CH:28]=1)[C:19]([O:21][CH2:22][CH3:23])=[O:20]>>[OH:17][C@H:18]([CH2:24][CH2:25][CH2:26][C:27]1[CH:28]=[CH:29][C:30]([O:33][CH3:34])=[CH:31][CH:32]=1)[C:19]([O:21][CH2:22][CH3:23])=[O:20]参加物
3
実験手順
Using (2R)-2-hydroxy-5-(4-methoxy-phenyl)pentanoic acid (80% e.e.), ethyl 2-hydroxy-5-(4-methoxyphenyl)pentanoate was quantitatively obtained (80% e.e.) by a process similar to the process described in Reference Example 27. The optical purity analysis conditions are as follows: Column: AD-H (Chiralcel, DAICEL Chemical Industries Ltd.)
後処理
- customwas quantitatively obtained (80% e.e.) by a process similar to the process
出典と根拠
- ORDレコード
- ord-1fd94ab8c6dd438695a4f077b219516d
- 出典データセット
- uspto-grants-2011_02
- 特許番号
- US07879843B2
反応ノート
読み込み中…