Phosphorus oxychloride → 6-(8-chloro-3-methyl-1,7-naphthyridin-4-yl)-N-methylquinazolin-2-amine

反応式

[CH3:1][c:2]1[cH:3][n:4][c:5]2[c:6](=[O:24])[nH:7][cH:8][cH:9][c:10]2[c:11]1-[c:12]1[cH:13][c:14]2[cH:15][n:16][c:17]([NH:22][CH3:23])[n:18][c:19]2[cH:20][cH:21]1.[P:25]([Cl:26])([Cl:27])([Cl:28])=[O:29]>>[CH3:1][c:2]1[cH:3][n:4][c:5]2[c:6]([Cl:27])[n:7][cH:8][cH:9][c:10]2[c:11]1-[c:12]1[cH:13][c:14]2[cH:15][n:16][c:17]([NH:22][CH3:23])[n:18][c:19]2[cH:20][cH:21]1

参加物

反応物 2

HCID 24813Phosphorus oxychloride

HCID 673399143-methyl-4-(2-(methylamino)quinazolin-6-yl)-1,7-naphthyridin-8(7H)-one

生成物 1

HCID 771748686-(8-chloro-3-methyl-1,7-naphthyridin-4-yl)-N-methylquinazolin-2-amine

出典と根拠

ORDレコード: ord-aec84e4db0ba40b399eab38cd63d0089
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…