2-Amino-N-phenylbenzamide → 2-[(2,5-Dichloro-4-pyrimidinyl)amino]-N-phenylbenzamide

反応式

[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[C:4]([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=[O:5].[Cl:17][C:18]1[N:23]=[C:22](Cl)[C:21]([Cl:25])=[CH:20][N:19]=1>>[Cl:17][C:18]1[N:23]=[C:22]([NH:1][C:2]2[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=2[C:4]([NH:6][C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[O:5])[C:21]([Cl:25])=[CH:20][N:19]=1

参加物

反応物 2

HCID 781422-Amino-N-phenylbenzamide

HCID 2372592,4,5-Trichloropyrimidine

生成物 1

HCID 579741332-[(2,5-Dichloro-4-pyrimidinyl)amino]-N-phenylbenzamide

実験手順

2-[(2,5-Dichloro-4-pyrimidinyl)amino]-N-phenylbenzamide was prepared from 2-amino-N-phenylbenzamide and 2,4,5-trichloropyrimidine using a procedure substantially as described for the preparation of Intermediate 1. Mass (M+H)+=358, 360.

出典と根拠

ORDレコード: ord-73ef78c07137471ea06ffd6205184e75
出典データセット: uspto-grants-2011_02
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07884098B2

反応ノート

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