(3-Bromophenyl)acetic acid → Ethyl 3-(bromophenyl)acetate
反応式
[CH2:1]([O:3][C:4](=[O:13])[CH2:5][C:6]1[CH:11]=[CH:10][C:9](Br)=[CH:8][CH:7]=1)[CH3:2].[Br:14]C1C=C(CC(O)=O)C=CC=1>>[CH2:1]([O:3][C:4](=[O:13])[CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([Br:14])[CH:7]=1)[CH3:2]参加物
3
実験手順
Employing the same general procedure as for the preparation of ethyl(4-bromophenyl)acetate (Compound A), 100 g (463 mmol) of 3-bromophenylacetic acid was converted into the title compound (yellow oil) using 2 g of conc. H2SO4 and 500 ml of ethanol. PMR (CDCl3): δ 1.26 (3H, t, J=7.0 Hz), 3.56 (2H, s), 4.16 (2H, q, J=7.0 Hz), 7.16-7.26 (2H, m), 7.38-7.46 (2H, m).
出典と根拠
- ORDレコード
- ord-f9d9123ba1f04c7494e0e6ceb5f56621
- 出典データセット
- uspto-grants-1998_03
- 特許番号
- US05723666
反応ノート
読み込み中…