N,N-Dimethylglycine → 1-{4-[1-methyl-2-oxo-2-(1-pyrrolidinyl)ethyl]phenyl}-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole
反応式
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([C:9](=[O:10])[N:11]2[CH2:12][CH2:13][CH2:14][CH2:15]2)[CH3:16])[cH:6][cH:7]1.[C:37](=[O:38])([O-:39])[O-:40].[CH3:30][N:31]([CH2:32][C:33](=[O:34])[OH:35])[CH3:36].[CH3:43][S:44]([CH3:45])=[O:46].[Cu:47][I:48].[F:17][C:18]([c:19]1[n:20][nH:21][c:22]2[c:27]1[CH2:26][CH2:25][CH2:24][CH2:23]2)([F:28])[F:29].[K+:41].[K+:42]>>[c:2]1(-[n:21]2[n:20][c:19]([C:18]([F:17])([F:28])[F:29])[c:27]3[c:22]2[CH2:23][CH2:24][CH2:25][CH2:26]3)[cH:3][cH:4][c:5]([CH:8]([C:9](=[O:10])[N:11]2[CH2:12][CH2:13][CH2:14][CH2:15]2)[CH3:16])[cH:6][cH:7]1
