1-Cyclooct-2-enylethanol → HCID 66957734、化合物
反応式
[CH:1]1([CH:9]([OH:11])[CH3:10])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH:3]=[CH:2]1.[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>ClCCl>[CH:1]1([C:9](=[O:11])[CH3:10])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH:3]=[CH:2]1参加物
4
反応条件
- 温度
- 20 °C
実験手順
At 0° C., a solution of 1-cyclooct-2-enylethanol (1.4 g, 9 mmol) in dichloromethane (20 ml) was added to pyridiniumchlorochromate (2.35 g, 11 mmol) in dichloromethane (30 ml). The resulting mixture was stirred at 20° C. during 3.5 h and filtered through Celite®. The filtrate was concentrated and the crude product purified by flash chromatography (hexane/Et2O 6:1) to give 0.7 g of 1-cyclooct-2-enylethanone (55%).
後処理
- filtrationfiltered through Celite®
- concentrationThe filtrate was concentrated
- customthe crude product purified by flash chromatography (hexane/Et2O 6:1)
出典と根拠
- ORDレコード
- ord-370f3edf77664681b0af7353941c8667
- 出典データセット
- uspto-grants-2011_02
- 特許番号
- US07888309B2
反応ノート
読み込み中…