N-(2-allyl-4-fluoro-phenyl)-acrylamide → HCID 57779786、化合物
反応式
[CH2:1]([C:4]1[CH:9]=[C:8]([F:10])[CH:7]=[CH:6][C:5]=1[NH:11][C:12](=[O:15])[CH:13]=[CH2:14])C=C>ClCCl>[F:10][C:8]1[CH:7]=[CH:6][C:5]2[NH:11][C:12](=[O:15])[CH:13]=[CH:14][CH2:1][C:4]=2[CH:9]=1参加物
3
実験手順
A round-bottom flask containing the product from Step 2 (4.51 g, 21.9 mmol) was fitted with a stirbar and septa. Dichloromethane (800 mL) and Zhan catalyst I (0.735 g, 1.11 mmol) were added, and the resulting solution was stirred for 18 hours at room temperature. The reaction was then concentrated in vacuo and recrystallized from dichloromethane to give the desired product.
後処理
- customwas fitted with a stirbar and septa
- concentrationThe reaction was then concentrated in vacuo
- customrecrystallized from dichloromethane
出典と根拠
- ORDレコード
- ord-3acdda58df154d9586e72789305e7edf
- 出典データセット
- uspto-grants-2011_02
- 特許番号
- US07888345B2
反応ノート
読み込み中…