4-(2-Bromoethylsulfonyl)benzonitrile → 4-(2-(4-methyl-1H-imidazole-1-yl)ethylsulfonyl)benzonitrile
反応式
Br[CH2:2][CH2:3][S:4]([C:7]1[CH:14]=[CH:13][C:10]([C:11]#[N:12])=[CH:9][CH:8]=1)(=[O:6])=[O:5].[CH3:15][C:16]1[N:17]=[CH:18][NH:19][CH:20]=1>>[CH3:15][C:16]1[N:17]=[CH:18][N:19]([CH2:2][CH2:3][S:4]([C:7]2[CH:14]=[CH:13][C:10]([C:11]#[N:12])=[CH:9][CH:8]=2)(=[O:6])=[O:5])[CH:20]=1参加物
3
実験手順
270 mg of 4-(2-bromoethylsulfonyl)benzonitrile was used in Procedure P with 4-methylimidazole to yield 4-(2-(4-methyl-1H-imidazole-1-yl)ethylsulfonyl)benzonitrile. 320 mg of 4-(2-(4-methyl-1H-imidazole-1-yl)ethylsulfonyl)benzonitrile was reacted via Procedure T to give 4-(2-(4-methyl-1H-imidazole-1-yl)ethylsulfonyl)benzoic acid.
出典と根拠
- ORDレコード
- ord-82041ddd9be642a08e20b317c57a02b1
- 出典データセット
- uspto-grants-2011_02
- 特許番号
- US07888364B2
反応ノート
読み込み中…