Sodium Bicarbonate → rac-2-(3,5-Bis-trifluoromethyl-phenyl)-N-[(3S,4R)-1-(1,1-dioxo-1-thiomorpholine-4-carbonyl)-4-(4-fluoro-phenyl)-pyrrolidin-3-yl]-N-methyl-isobutyramide

反応式

[F:1][C:2]([F:41])([F:40])[C:3]1[CH:4]=[C:5]([C:13]([CH3:39])([CH3:38])[C:14]([N:16]([C@H:18]2[C@H:22]([C:23]3[CH:28]=[CH:27][C:26]([F:29])=[CH:25][CH:24]=3)[CH2:21][N:20]([C:30]([N:32]3[CH2:37][CH2:36]S[CH2:34][CH2:33]3)=[O:31])[CH2:19]2)[CH3:17])=[O:15])[CH:6]=[C:7]([C:9]([F:12])([F:11])[F:10])[CH:8]=1.[OH:42][S:43]([O-:46])(=O)=O.OS(O[O-])(=O)=O.OS(O[O-])(=O)=O.[O-]S([O-])(=O)=O.[K+].[K+].[K+].[K+].[K+].OS([O-])=O.[Na+].C([O-])(O)=O.[Na+]>CO>[F:12][C:9]([F:10])([F:11])[C:7]1[CH:6]=[C:5]([C:13]([CH3:39])([CH3:38])[C:14]([N:16]([C@H:18]2[C@H:22]([C:23]3[CH:28]=[CH:27][C:26]([F:29])=[CH:25][CH:24]=3)[CH2:21][N:20]([C:30]([N:32]3[CH2:37][CH2:36][S:43](=[O:46])(=[O:42])[CH2:34][CH2:33]3)=[O:31])[CH2:19]2)[CH3:17])=[O:15])[CH:4]=[C:3]([C:2]([F:1])([F:40])[F:41])[CH:8]=1