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HRID 1367537作成日：2026年10月25日

4-Fluorophenol → (1R,2R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-(4-fluoro-phenoxymethyl)-cyclopentanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/1367537

反応式

関与物質

役割名称HCID仕込み量
反応物4-FluorophenolHCID 9732—
反応物(1R,2R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-hydroxymethyl-cyclopentanecarboxylic acid ethyl esterHCID 59619451—
生成物(1R,2R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-(4-fluoro-phenoxymethyl)-cyclopentanecarboxylic acid ethyl esterHCID 66919037—

反応手順

The title compound was prepared in analogy to example 68 step 5 using (1R,2R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-hydroxymethyl-cyclopentanecarboxylic acid ethyl ester (example 68 step 4) and 4-fluorophenol. Colorless oil (74%). MS (EI): 397.2 (M+H)+.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07893099B2
出典データセットuspto-grants-2011_02
ORD IDord-9e0b5b62a35f4d3ba0d86c31311deb1b
出典メモuspto-grants-2011_02