化工社化工社 化学情報印刷レポート · 研究参考用
Triethyl orthoacetate → 4(3H)-Quinazolinone, 2-methyl-3-(2-pyridyl)-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethyl orthoacetate | HCID 66221 | — |
| 反応物 | 2-amino-N-(pyridin-2-yl)benzamide | HCID 276325 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 4(3H)-Quinazolinone, 2-methyl-3-(2-pyridyl)- | HCID 64049 | 75% |
反応手順
A mixture of 72 (3 g, 0.015 mol) and 1,1,1-triethoxy-ethane (5 g, 0.045 mol) were heated for 7 hours. The reaction mixture was poured into water, filtered, and the precipitate was washed with water and recrystallized from EtOH to yield 73 (2.5 g, 75%). M. Wt. 237. LCMS [M+H]+=238.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07893260B2 |
| 出典データセット | uspto-grants-2011_02 |
| ORD ID | ord-52413c69eb47490895aba0999c6e30a4 |
| 出典メモ | uspto-grants-2011_02 |