Isopropyl iodide → HCID 178458193、化合物

HRID 1368536ノート

反応式

HRID 1368536 の反応式
[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([C:12]([C:17]1[N:18]=[CH:19][N:20](C(C3C=CC=CC=3)(C3C=CC=CC=3)C3C=CC=CC=3)[CH:21]=1)([OH:16])[CH:13]([CH3:15])[CH3:14])[CH:6]=[CH:5]2.[CH:41](I)([CH3:43])[CH3:42]>>[CH:41]([O:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([C:12]([C:17]1[N:18]=[CH:19][NH:20][CH:21]=1)([OH:16])[CH:13]([CH3:14])[CH3:15])[CH:6]=[CH:5]2)([CH3:43])[CH3:42]

参加物

3

反応物 2

HCID 6362Isopropyl iodideHCID 220183856-(1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl)-2-naphthol

生成物 1

HCID 178458193HCID 178458193、化合物

実験手順

In a similar manner to that described in Example 31-(i), the reaction of 1-(6-hydroxynaphthalen-2-yl)-2-methyl-1-(1-trityl-1H-imidazol-4-yl)-1-propanol (0.965 g) with isopropyl iodide (0.20 ml) was carried out to give the titled compound (0.548 g) as a colorless solid.

出典と根拠

ORDレコード
ord-52f35c555a834b23a2173b61a8947fdd
出典データセット
uspto-grants-2003_06
特許番号
US06573289B1

反応ノート

読み込み中…