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1-(Thiophen-3-yl)ethanone → 3-Dimethylamino-1-thien-3-ylpropen-1-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(Thiophen-3-yl)ethanone | HCID 15116 | — |
| 反応物 | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| 生成物 | 3-Dimethylamino-1-thien-3-ylpropen-1-one | HCID 596466 | — |
反応手順
3-dimethylamino-1-thien-3-ylpropen-1-one was prepared from 3-acetylthiophene (15.0 g) and dimethylformamide dimethylacetal (47.5 mL, 357 mmol) as a yellow solid (14 g), m.p. 98°. δH (CDCl3) 7.90 (1H, dd, J 3.0, 1.0 Hz), 7.76 (1H, d, J 12.4 Hz), 7.53 (1H, dd, J 5.9,1.0 Hz), 7.28-7.25 (1H, m), 5.57 (1H,d, J 12.4 Hz) and 3.03 (6H, bs).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06579983B1 |
| 出典データセット | uspto-grants-2003_06 |
| ORD ID | ord-ee06bd1fdb374742ae23ed07826de3d5 |
| 出典メモ | uspto-grants-2003_06 |