7-Bromoindole → 7-Bromo-3-(1-ethyl-5-fluoro-indan-1-yl)-1H-indole

関与物質

役割	名称	HCID	仕込み量
反応物	7-Bromoindole	HCID 2757020	—
反応物	1-Ethyl-5-fluoroindan-1-ol	HCID 59340428	—
生成物	7-Bromo-3-(1-ethyl-5-fluoro-indan-1-yl)-1H-indole	HCID 11530547	—

反応手順

Utilizing 1-ethyl-5-fluoro-indan-1-ol and 7-bromoindole, the title compound is prepared as in example 1. 51 mg (16%). NMR (400 MHz, CDCl3): δ 0.82 (t, 3H), 2.12 (m, 1H), 2.21 (m, 1H), 2.30 (m, 1H), 2.59 (m, 1H), 2.97 (m, 2H), 6.82 (m, 2H), 6.90 (s, 1H), 6.99 (m, 2H), 7.12 (d, 1H), 7.28 (d, 1H), 8.08 (s, 1H, NH).

情報源と証拠

DOI	10.6084/m9.figshare.5104873.v1
特許番号	US07728150B2
出典データセット	uspto-grants-2010_06
ORD ID	ord-ad3fb49b57844c22a07f4f82e525d931
出典メモ	uspto-grants-2010_06