(1H-Indol-7-yl)-carbamic acid benzyl ester → [3-(1-Ethyl-5-fluoro-indan-1-yl)-1H-indol-7-yl]-carbamic acid benzyl ester

HRID 13711

反応式

HRID 13711 の反応式
[CH2:1]([C:3]1(O)[C:11]2[C:6](=[CH:7][C:8]([F:12])=[CH:9][CH:10]=2)[CH2:5][CH2:4]1)[CH3:2].[CH2:14]([O:21][C:22](=[O:33])[NH:23][C:24]1[CH:25]=[CH:26][CH:27]=[C:28]2[C:32]=1[NH:31][CH:30]=[CH:29]2)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH2:14]([O:21][C:22](=[O:33])[NH:23][C:24]1[CH:25]=[CH:26][CH:27]=[C:28]2[C:32]=1[NH:31][CH:30]=[C:29]2[C:3]1([CH2:1][CH3:2])[C:11]2[C:6](=[CH:7][C:8]([F:12])=[CH:9][CH:10]=2)[CH2:5][CH2:4]1)[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

参加物

3

反応物 2

HCID 24749680(1H-Indol-7-yl)-carbamic acid benzyl esterHCID 593404281-Ethyl-5-fluoroindan-1-ol

生成物 1

HCID 58941681[3-(1-Ethyl-5-fluoro-indan-1-yl)-1H-indol-7-yl]-carbamic acid benzyl ester

実験手順

Utilizing 1-ethyl-5-fluoro-indan-1-ol and (1H-indol-7-yl)-carbamic acid benzyl ester, the tide compound is prepared as in example 1. 7.78 g (100%). LC-MS m/z 249.1 (M++1)

後処理

  1. customthe tide compound is prepared as in example 1

出典と根拠

ORDレコード
ord-504e1392ceb44dfab6162ce61aa50c82
出典データセット
uspto-grants-2010_06
特許番号
US07728150B2

関連ノート

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