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2,6-Dichloro-4-isocyanatopyridine → N-{[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}N'-(2,6-dichloropyridin-4-yl)urea
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,6-Dichloro-4-isocyanatopyridine | HCID 2781658 | — |
| 反応物 | [4-(3,4-Dichlorobenzyl)morpholin-2-yl]methylamine | HCID 10308229 | — |
| 生成物 | N-{[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}N'-(2,6-dichloropyridin-4-yl)urea | HCID 10183254 | 39.1% |
反応手順
Example 24 was prepared in an analogous manner to Example 1 using a mixture of Intermediate 3 (0.025 g) and 2,6-dichloro-4-isocyanatopyridine (0.0258 g) to give the title compound (0.0165 g). LC-MS (System A): Rt 2.46 mins, Mass Spectrum m/z 463 [MH+].
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07157457B2 |
| 出典データセット | uspto-grants-2007_01 |
| ORD ID | ord-fb45000ffe6b4b209ec323ca48bb05f5 |
| 出典メモ | uspto-grants-2007_01 |