3-Nitrodibenzofuran → 3-Dibenzofuranamine
反応式
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]2[C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=3[O:9][C:8]=2[CH:16]=1)([O-])=O>[Ni].C(O)C>[CH:6]1[C:7]2[C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=3[O:9][C:8]=2[CH:16]=[C:4]([NH2:1])[CH:5]=1参加物
4
実験手順
Combine 3-nitrodibenzofuran (22.0 g, 0.1 mol) and Raney nickel (2.75 g), and ethanol (365 ml) and hydrogenate at room temperature and 40 psi (276 kPa). After 18 hours, filter and concentrate the filtrate to residue. Chromatograph the residue eluting with 9:1 hexane:EtOAc to give the title compound.
後処理
- customhydrogenate at room temperature
- filtrationfilter
- concentrationconcentrate the filtrate to residue
- washChromatograph the residue eluting with 9:1 hexane
出典と根拠
- ORDレコード
- ord-9738013b52af4902825d241884ee1d3d
- 出典データセット
- uspto-grants-2007_01
- 特許番号
- US07157488B2
反応ノート
読み込み中…