化工社化工社 化学情報印刷レポート · 研究参考用
4-Fluorobenzylic alcohol → 4-Fluorobenzoic Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Fluorobenzylic alcohol | HCID 68022 | — |
| 反応物 | Sodium Bromate | HCID 23668195 | — |
| 溶媒 | Acetonitrile--water (1/1) | HCID 18373917 | — |
| 生成物 | 4-Fluorobenzoic Acid | HCID 9973 | 89.7% |
反応手順
The separated catalyst was added to a fresh batch of sodium bromate (0.3 g) and 4-fluorobenzyl alcohol (0.256 g, 2 mmol) in acetonitrile:water (1:1, 10 ml). The above procedure was repeated to give 4-fluorobenzoic acid as a white solid (0.25 g, 88%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07728159B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-3613e9979b044dd4a9ed5815f48c5a94 |
| 出典メモ | uspto-grants-2010_06 |