Triphenylphosphine → (3-Methoxybenzyl)triphenylphosphonium Chloride

HRID 1374845ノート

反応式

HRID 1374845 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH2:6][Cl:7].[C:11]1([P:17]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>CN(C)C=O>[Cl-:7].[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH2:6][P+:17]([C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1)([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1

参加物

4

反応物 2

HCID 11776TriphenylphosphineHCID 699943-Methoxybenzyl chloride

生成物 1

HCID 11407464(3-Methoxybenzyl)triphenylphosphonium Chloride収率 61%

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

反応条件

温度
150 °C

実験手順

3-Methoxybenzyl chloride (1.05 g, 6.69 mmol), triphenylphosphine (1.75 g, 6.67 mmol) was dissolved in dimethylformamide (10 ml) and heated at 150° C. for 40 minutes. The reaction mixture was cooled to room temperature, and the solid precipitated was collected by filtration and washed and ethyl ether, and then dried under reduced pressure to obtain the title compound as colorless solid 1.70 g (yield: 61%).

後処理

  1. temperatureThe reaction mixture was cooled to room temperature
  2. customthe solid precipitated
  3. filtrationwas collected by filtration
  4. washwashed
  5. dry with materialethyl ether, and then dried under reduced pressure

出典と根拠

ORDレコード
ord-dd329a8845a841a2858c3b6ba450995c
出典データセット
uspto-grants-2007_01
特許番号
US07166617B2

反応ノート

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