Hydrochloric Acid → 5-Amino-2-methoxy-5-methylhex-3-yne hydrochloride

HRID 1374909ノート

反応式

HRID 1374909 の反応式
[CH3:1][O:2][CH:3]([C:5]#[C:6][C:7]([N:10]1[Si](C)(C)CC[Si]1(C)C)([CH3:9])[CH3:8])[CH3:4].[ClH:19]>>[ClH:19].[NH2:10][C:7]([CH3:9])([CH3:8])[C:6]#[C:5][CH:3]([O:2][CH3:1])[CH3:4]

参加物

3

反応物 2

HCID 313Hydrochloric AcidHCID 21078409(2-Methoxy-5-methylhex-3-yn-5-yl)-2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane

生成物 1

HCID 210784255-Amino-2-methoxy-5-methylhex-3-yne hydrochloride

実験手順

(2-Methoxy-5-methylhex-3-yn-5-yl)-2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane (1.2 g) was stirred with dilute aqueous hydrochloric acid (12 ml) for 0.25 hours. The aqueous phase was washed with diethyl ether (twice) and the evaporated under reduced pressure. The residue was evaporated with toluene (twice) to remove residual water to give 5-amino-2-methoxy-5-methylhex-3-yne hydrochloride, 0.54 g, as a yellow solid.

後処理

  1. washThe aqueous phase was washed with diethyl ether (twice) and the
  2. customevaporated under reduced pressure
  3. customThe residue was evaporated with toluene (twice)
  4. customto remove residual water

出典と根拠

ORDレコード
ord-f4899fa024e248c28d01fcf05223a0e6
出典データセット
uspto-grants-2007_01
特許番号
US07166621B2

反応ノート

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