2-(5-Chloro-3-pyridyloxy)butyric acid → 2-(5-chloro-3-pyridyloxy)-N-(2-methoxy-5-methylhex-3-yn-5-yl)butyramide

HRID 1374910ノート

反応式

HRID 1374910 の反応式
Cl.[NH2:2][C:3]([CH3:11])([CH3:10])[C:4]#[C:5][CH:6]([O:8][CH3:9])[CH3:7].[Cl:12][C:13]1[CH:14]=[C:15]([O:19][CH:20]([CH2:24][CH3:25])[C:21](O)=[O:22])[CH:16]=[N:17][CH:18]=1>>[Cl:12][C:13]1[CH:14]=[C:15]([O:19][CH:20]([CH2:24][CH3:25])[C:21]([NH:2][C:3]([CH3:11])([CH3:10])[C:4]#[C:5][CH:6]([O:8][CH3:9])[CH3:7])=[O:22])[CH:16]=[N:17][CH:18]=1

参加物

3

反応物 2

HCID 210783782-(5-Chloro-3-pyridyloxy)butyric acidHCID 210784255-Amino-2-methoxy-5-methylhex-3-yne hydrochloride

生成物 1

HCID 210783842-(5-chloro-3-pyridyloxy)-N-(2-methoxy-5-methylhex-3-yn-5-yl)butyramide

実験手順

5-Amino-2-methoxy-5-methylhex-3-yne hydrochloride was reacted with 2-(5-chloro-3-pyridyloxy)butyric acid in a similar procedure to Example 1, Stage 3 to give 2-(5-chloro-3-pyridyloxy)-N-(2-methoxy-5-methylhex-3-yn-5-yl)butyramide as a yellow oil.

出典と根拠

ORDレコード
ord-fca56104198a4b5b96d1612f2210f170
出典データセット
uspto-grants-2007_01
特許番号
US07166621B2

反応ノート

読み込み中…