Maleic Anhydride → 3-(Sec-butylcarbamoyl)acrylic acid

HRID 1375213

反応式

HRID 1375213 の反応式
[C:1]1(=[O:7])[O:6][C:4](=[O:5])[CH:3]=[CH:2]1.[CH:8]([NH2:12])([CH2:10][CH3:11])[CH3:9]>C(OCC)C>[CH:8]([NH:12][C:1]([CH:2]=[CH:3][C:4]([OH:6])=[O:5])=[O:7])([CH2:10][CH3:11])[CH3:9]

参加物

4

反応物 2

HCID 7923Maleic AnhydrideHCID 24874Sec-Butylamine

生成物 1

HCID 2445953-(Sec-butylcarbamoyl)acrylic acid

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒2 回

実験手順

To a stirred solution of maleic anhydride, 95% (42.1 g, 0.4 mol) in 500 mL diethyl ether at 0° C. was added drop wise sec-butyl amine (29.25 g, 0.4 mol) in 50 mL diethyl ether. The resulting mixture was stirred while a solid formed, which was recovered by filtration. The residue was washed with 2×100 mL diethyl ether and dried to yield 51.76 g of the desired compound.

後処理

  1. customformed
  2. filtrationwhich was recovered by filtration
  3. washThe residue was washed with 2×100 mL diethyl ether
  4. customdried

出典と根拠

ORDレコード
ord-073bcdb2231e4176a7b6e35ccdf4ce32
出典データセット
uspto-grants-2007_01
特許番号
US07166748B2

関連ノート

読み込み中…