Tin tetrachloride → Ethyl 4-[1-(6-methyl-pyrid-3-yl)-3,4-dihydro-4,4-dimethyl-anthracen-8-yl]-benzoate

反応式

[CH3:1][C:2]1S[C:5]([C:7]2[C:20]3[C:11](=[CH:12][C:13]4[C:18]([CH:19]=3)=[C:17]([C:21]3[CH:31]=[CH:30][C:24]([C:25]([O:27][CH2:28][CH3:29])=[O:26])=[CH:23][CH:22]=3)[CH:16]=[CH:15][CH:14]=4)[C:10]([CH3:33])([CH3:32])[CH2:9][CH:8]=2)=[CH:4][CH:3]=1.C[C:35]1C=CC(C2(C=O)C3C(=CC=CC=3)C(C)(C)CC2)=C[N:36]=1.C(OP(C(OC)(OC)CCC1C=CC(C(OCC)=O)=CC=1)(OCC)=O)C.COC(OC)C/C(/C1C=CC(C(OCC)=O)=CC=1)=C\C1C=C2C(C(C)(C)CC=C2C2C=CC(C)=CC=2)=CC=1.Cl[Sn](Cl)(Cl)Cl>ClCCl>[CH3:1][C:2]1[N:36]=[CH:35][C:5]([C:7]2[C:20]3[C:11](=[CH:12][C:13]4[C:18]([CH:19]=3)=[C:17]([C:21]3[CH:31]=[CH:30][C:24]([C:25]([O:27][CH2:28][CH3:29])=[O:26])=[CH:23][CH:22]=3)[CH:16]=[CH:15][CH:14]=4)[C:10]([CH3:33])([CH3:32])[CH2:9][CH:8]=2)=[CH:4][CH:3]=1

参加物

実験手順

This compound is prepared in accordance with the procedure described for the preparation of ethyl 4-[1(5-methyl-thien-2-yl)3,4-dihydro-4,4-dimethyl-anthracen-8-yl]-benzoate (Compound 3), from 1(2-methyl-pyrid-5-yl)3,4-dihydro-4,4-dimethyl-naphthaldehyde (Compound K) by reaction with ethyl 4-(diethoxyphosphoryl-3,3-dimethoxypropyl)benzoate (Compound D) and proceeding through the intermediate ethyl 4-[1-(2,2-dimethoxyethyl)-2-{1-(tol-4-yl)3,4-dihydro-4,4-dimethyl-naphthalen-7-yl}-(E)-ethen-1-yl]-benzoate which is cyclized by treatment with SnCl4 in dichloromethane to give the title compoud.

後処理

customThis compound is prepared in accordance with the procedure
customto give the title compoud

出典と根拠

ORDレコード: ord-bc4b7bd7985d4541a8c639f8cc3c3758
出典データセット: uspto-grants-2007_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07166726B2

反応ノート

読み込み中…

反応式

参加物

反応物 5

生成物 1

試薬・触媒・溶媒 1

実験手順

後処理

出典と根拠

反応ノート