関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 3-Methoxybenzylamine | HCID 21156 | — |
| 反応物 | 3-Methoxybenzyl isothiocyanate | HCID 126512 | — |
| 反応物 | 1-(3-Methoxybenzyl)-2-thiourea | HCID 2759541 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 1,3-Di(3-Methoxybenzyl) Thiourea | HCID 10267842 | — |
反応手順
The reaction of 3-methoxybenzyl isothiocyanate with 3-methoxybenzyl amine in ethanol was repeated doubling the reaction volume and reactants and heating for 2 h at 40° C. Crystallization at −10° C., followed by evaporation of the supernatant to 20 ml and a second crystallization gave 98.4% of the theoretical yield for the two crystallizations combined. Calculated elemental analysis of 3-methoxybenzyl thiourea: C, 64.53; H, 6.37; N, 8.85; S, 10.13. Found: C, 64.30; H, 6.46; N, 8.85; S, 10.09.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07169815B2 |
|---|
| 出典データセット | uspto-grants-2007_01 |
|---|
| ORD ID | ord-55d71da4d1834758a3059e3f91977add |
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| 出典メモ | uspto-grants-2007_01 |
|---|
