tert-Butyl piperazine-1-carboxylate → HCID 58780713、化合物

HRID 1376061ノート

反応式

HRID 1376061 の反応式
[N+:1]([CH:4]=[CH:5][CH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)([O-:3])=[O:2].[C:12]([N:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1)([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:13]>C(Cl)Cl>[C:15]([O:14][C:12]([N:19]1[CH2:24][CH2:23][N:22]([CH:5]([CH:6]2[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]2)[CH2:4][N+:1]([O-:3])=[O:2])[CH2:21][CH2:20]1)=[O:13])([CH3:18])([CH3:16])[CH3:17]

参加物

4

反応物 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 66992131(2-Nitrovinyl)-cyclohexane

生成物 1

HCID 58780713HCID 58780713、化合物収率 99%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To a solution of (2-nitrovinyl)-cyclohexane (2.63 g, 16.94 mmol), prepared as in J. Org. Chem. 1993, 58, 3850, in dry CH2Cl2 (22 mL), N-Boc piperazine (2.63 g, 14.12 mmol) was added at room temperature and reaction stirred overnight. Solvent was removed under reduced pressure to afford the adduct product (99%) as an oil. MS m/z 342.4 (M++1) .

後処理

  1. customreaction
  2. customSolvent was removed under reduced pressure

出典と根拠

ORDレコード
ord-3d306851976b4c00835fdb3645c9129e
出典データセット
uspto-grants-2007_01
特許番号
US07169777B2

反応ノート

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