1-(4-Fluorophenyl)piperazine → N-(1-methyl-1-(4-((4-(4-fluorophenyl)-piperazin-1-yl)methyl)phenyl)ethyl)acetamide

反応式

[Cl:14][CH2:15][c:16]1[cH:17][cH:18][c:19]([C:22]([CH3:23])([CH3:24])[NH:25][C:26]([CH3:27])=[O:28])[cH:20][cH:21]1.[F:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([CH2:15][c:16]3[cH:17][cH:18][c:19]([C:22]([CH3:23])([CH3:24])[NH:25][C:26]([CH3:27])=[O:28])[cH:20][cH:21]3)[CH2:12][CH2:13]2)[cH:6][cH:7]1

参加物

反応物 2

HCID 752601-(4-Fluorophenyl)piperazine

HCID 18423089N-(1-(4-chloromethylphenyl)-1-methylethyl)acetamide

生成物 1

HCID 11545168N-(1-methyl-1-(4-((4-(4-fluorophenyl)-piperazin-1-yl)methyl)phenyl)ethyl)acetamide

出典と根拠

ORDレコード: ord-45bae394266a4bac866701d565d4bf6b
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…