Methylamine → HCID 22918634、化合物
反応式
[CH2:1]([N:8]1[C:12](Br)=[C:11]([N+:14]([O-:16])=[O:15])[C:10]([Br:17])=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:18][NH2:19]>O>[CH2:1]([N:8]1[C:12]([NH:19][CH3:18])=[C:11]([N+:14]([O-:16])=[O:15])[C:10]([Br:17])=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
4
実験手順
3.61 g (10 mmoles) of 1-benzyl -3,5-dibromo-4-nitropyrazole are heated in 100 ml of a 35-percent solution of methylamine in water for 4 hours at 60° C. After cooling, the separated precipitate is collected by filtration and recrystallized once from ethanol. 2.7 g (87 percent of theory) of 1-benzyl-3-bromo-5-methylamino-4-nitropyrazole are obtained in the form of colorless crystals with a melting point of 116° C.
後処理
- temperatureAfter cooling
- filtrationthe separated precipitate is collected by filtration
- customrecrystallized once from ethanol
出典と根拠
- ORDレコード
- ord-247c1dad6cd749e790798edac8c27bb3
- 出典データセット
- uspto-grants-1997_09
- 特許番号
- US05663366
反応ノート
読み込み中…