Sulfuric Acid → 2-((4-Amino-1-methyl-1H-pyrazol-5-yl)amino)ethanol
反応式
Br[C:2]1[C:6]([N+:7]([O-])=O)=[C:5]([NH:10][CH2:11][CH2:12][OH:13])[N:4]([CH3:14])[N:3]=1.S(=O)(=O)(O)O>O>[NH2:7][C:6]1[CH:2]=[N:3][N:4]([CH3:14])[C:5]=1[NH:10][CH2:11][CH2:12][OH:13]参加物
4
実験手順
1 g (3.77 mmoles) of 3-bromo-5-(2'-hydroxyethyl)amino-1-methyl-4-nitropyrazole are hydrogenated in a solution of 380 mg (3.77 mmoles) sulfuric acid in 50 ml water for 2 hours according to method (2). 720 mg (75 percent of theory) of 4-amino-5-(2'-hydroxyethyl)amino-1-methylpyrazole hydrosulfate are obtained in the form of colorless crystals with a melting point of 94° to 97° C.
出典と根拠
- ORDレコード
- ord-dd9ff91ed6314efea24e52902df4b423
- 出典データセット
- uspto-grants-1997_09
- 特許番号
- US05663366
反応ノート
読み込み中…