Dimethylformamide → 4-(Bromomethyl)-5-methyl-1,3-dioxol-2-one

To 403 mg of 4-(chloromethyl)-5-methyl-1,3-dioxol-2-one and 525 mg of sodium bromide was added 0.8 ml of anhydrous N,N-dimethylformamide, followed by at room temperature for 1.5 hours. To the reaction solution was added 1.2 ml anhydrous acetone, the mixture was further stirred at room temperature for 1 hour, and then insolubles were removed by filtration. Insolubles were washed three times with 0.8 ml of anhydrous acetone, and the resulting pale yellow solution was used in the next reaction.

1. custominsolubles were removed by filtration
2. washInsolubles were washed three times with 0.8 ml of anhydrous acetone
3. customthe resulting pale yellow solution was used in the next reaction

ORDレコード

ord-7673f946ac5a4594919a73190681f2f3

出典データセット

uspto-grants-2010_06

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US07728131B2