化工社化工社 化学情報印刷レポート · 研究参考用
Imatinib amine → 4-(1-methylpiperidin-4-ylidenemethyl)-3-trifluoromethyl-N-{4-methyl-3-[4-(3-pyridyl)pyrimidin-2-ylamino]phenyl}benzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Imatinib amine | HCID 9965429 | — |
| 反応物 | HCID 23145987 | HCID 23145987 | — |
| 生成物 | 4-(1-methylpiperidin-4-ylidenemethyl)-3-trifluoromethyl-N-{4-methyl-3-[4-(3-pyridyl)pyrimidin-2-ylamino]phenyl}benzamide | HCID 11238319 | — |
反応手順
This compound was prepared in the same manner as in Example 1, except that 4-methyl-3-[4-(3-pyridyl)pyrimidin-2-ylamino]aniline (Patent Document 1) and 4-(1-methylpiperidin-4-ylidenemethyl)-3-trifluoromethylbenzoyl chloride hydrochloride (Reference Example 7) were used.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07728131B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-c95c08d962704b3494c2f6728b0eb2e3 |
| 出典メモ | uspto-grants-2010_06 |