Water → HCID 178442356、化合物

HRID 1380569ノート

反応式

HRID 1380569 の反応式
[Cl:1][C:2]1=[C:3]([Cl:9])[C:4]([O:6][C:7]1=[O:8])=[O:5].[C:10]1([C:16]([CH3:22])([CH3:21])[CH2:17][CH:18]([NH2:20])[CH3:19])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.O>C(O)(=O)C>[C:10]1([C:16]([CH3:21])([CH3:22])[CH2:17][CH:18]([N:20]=[C:4]([OH:5])/[C:3](/[Cl:9])=[C:2](/[Cl:1])\[C:7]([OH:6])=[O:8])[CH3:19])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

参加物

5

反応物 3

HCID 962WaterHCID 70728Dichloromaleic anhydrideHCID 13290299(1,3-dimethyl-3-phenylbutyl)amine(SALTDATA: HCl)

生成物 1

HCID 178442356HCID 178442356、化合物収率 682.7%

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

反応条件

温度
20 °C

実験手順

16.7 g (0.1 mol) of dichloromaleic anhydride and 17.7 g (0.01 mol) of 3-phenyl-1,3,3-trimethylpropylamine are stirred in 100 ml of glacial acetic acid under reflux for 4 hours. 50 ml of water are added and the mixture is cooled to 20° C. The product is filtered off with suction and dried. 23.5 g (72% of theory) of dichloromaleic acid N-(3-phenyl-1,3,3-trimethylpropyl)-imide of melting point 106°-109° C. are obtained.

後処理

  1. temperatureunder reflux for 4 hours
  2. filtrationThe product is filtered off with suction
  3. customdried

出典と根拠

ORDレコード
ord-97502894486c4d1282e18e1f9c9c1fd3
出典データセット
uspto-grants-1986_04
特許番号
US04582849

反応ノート

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