関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 2,3-Diaminopyridine | HCID 9956 | — |
| 反応物 | 4-Amino-o-anisic acid | HCID 75599 | — |
| 反応物 | 4-(Chlorosulfonyl)-2-methoxybenzoic acid | HCID 20184580 | — |
| 溶媒 | Phosphorus oxychloride | HCID 24813 | — |
| 生成物 | HCID 178493630 | HCID 178493630 | — |
反応手順
Five grams of 2-methoxy-4-chlorosulfonyl-benzoic acid (prepared from 4-amino-2-methoxy-benzoic acid via the corresponding diazonium compound) were dissolved in 400 ml of phosphorus oxychloride and heated to 80° C. for 30 minutes. Then, 3.6 gm of 2,3-diaminopyridine were added, and the mixture was refluxed for four hours. The reaction mixture was concentrated by evaporation in vacuo and re-evaporated with toluene, and the solid residue was processed further without any other purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04582837 |
|---|
| 出典データセット | uspto-grants-1986_04 |
|---|
| ORD ID | ord-94633bad767d4d8fbfd17521349fbbb8 |
|---|
| 出典メモ | uspto-grants-1986_04 |
|---|
