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4,5-Diaminopyrimidine → 2-(2'-Methoxy-4'-chlorosulfonyl-phenyl)-purine hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4,5-Diaminopyrimidine | HCID 83703 | — |
| 反応物 | 4-(Chlorosulfonyl)-2-methoxybenzoic acid | HCID 20184580 | — |
| 生成物 | 2-(2'-Methoxy-4'-chlorosulfonyl-phenyl)-purine hydrochloride | HCID 20184529 | — |
反応手順
Prepared analogously to Example C from 2.5 gm of 2-methoxy-4-chlorosulfonyl benzoic acid and 2.4 gm of 4,5-diamino-pyrimidine (crystalline product obtained from dihydorchloride and 1 mol of common salt) by refluxing for eight hours. The solid crude product was processed further without any purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04582837 |
| 出典データセット | uspto-grants-1986_04 |
| ORD ID | ord-6d842c7706d44ef9bc1746be111d8ca0 |
| 出典メモ | uspto-grants-1986_04 |