Ethanol → Ethyl 3-methoxy-4-(7H-purin-8-yl)benzoate
反応式
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([C:9](N)=[O:10])[CH:6]=[CH:5][C:4]=1[C:12]1[NH:20][C:19]2[C:14](=[N:15][CH:16]=[N:17][CH:18]=2)[N:13]=1.[CH2:21]([OH:23])[CH3:22]>>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([C:9]([O:23][CH2:21][CH3:22])=[O:10])[CH:6]=[CH:5][C:4]=1[C:12]1[NH:20][C:19]2[C:14](=[N:15][CH:16]=[N:17][CH:18]=2)[N:13]=1参加物
3
実験手順
A quantity of 0.42 gm of 8-(2'-methoxy-4'-chlorocarbonyl-phenyl)-purine hydrochloride (see Example 43) was refluxed in 30 ml of ethanol for 45 minutes. The solvent was evaporated off, and the residue was purified over a silica gel column [eluant: methylene chloride/ethanol (50:1 to 19:1)].
後処理
- customThe solvent was evaporated off
- customthe residue was purified over a silica gel column [eluant: methylene chloride/ethanol (50:1 to 19:1)]
出典と根拠
- ORDレコード
- ord-441c04dd5d6a457d8d41d361bc4b29a7
- 出典データセット
- uspto-grants-1986_04
- 特許番号
- US04582837
反応ノート
読み込み中…