Water → HCID 13491011、化合物
反応式
[CH:1](=O)[C:2]([CH3:5])([CH3:4])[CH3:3].[CH3:7][NH:8][C:9](=[O:15])[C@H:10]([CH:12]([CH3:14])[CH3:13])[NH2:11].O>CCCCC>[CH3:7][NH:8][C:9](=[O:15])[C@H:10]([CH:12]([CH3:14])[CH3:13])[N:11]=[CH:1][C:2]([CH3:5])([CH3:4])[CH3:3]参加物
5
実験手順
There were added 95.7 ml (870 mmols) of pivalaldehyde to 112.0 grams (864 mmoles) of (S)-valine monomethylamide dissolved in 300 ml of n-pentane. The reaction mixture was boiled at a water separator until the formation of water was ended (4 hours). The solvent was removed under reduced pressure and there remained behind 130 grams (76% of theory) of (S)-N-(2',2'-dimethyl-propylidene)-valine monomethylamide, which could be further worked without purification. To ascertain the exact material data, a test of sample was purified by distillation.
後処理
- custom(4 hours)
- customThe solvent was removed under reduced pressure
- customcould be further worked without purification
- distillationa test of sample was purified by distillation
出典と根拠
- ORDレコード
- ord-a1601df2703b4002ab9685e07e65ff28
- 出典データセット
- uspto-grants-1986_04
- 特許番号
- US04585892
反応ノート
読み込み中…