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4-Toluenesulfonyl chloride → N,N-dimethyl-N'-(2,3-dihydrobenzofuran-2-ylmethyl)-1,3-propanediamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| 反応物 | N,N-Dimethyl-1,3-propanediamine | HCID 7993 | — |
| 反応物 | 2-Allylphenol | HCID 15624 | — |
| 反応物 | p-Toluenesulfonate | HCID 85570 | — |
| 反応物 | (2,3-Dihydro-1-benzofuran-2-yl)methanol | HCID 2795428 | — |
| 生成物 | N,N-dimethyl-N'-(2,3-dihydrobenzofuran-2-ylmethyl)-1,3-propanediamine | HCID 14099475 | — |
反応手順
The starting diamine of formula II can be prepared according to known processes; for example starting from 2-allylphenol, which is then converted to 2,3-dihydrobenzofuran-2-yl-methanol by the action of a peracid and subsequently to the tosylate by the action of para-toluene-sulphonyl chloride, the said tosylate then being reacted with 3-(dimethylamino)-propylamine to give N,N-dimethyl-N'-(2,3-dihydro-benzofuran-2-ylmethyl)-1,3-propanediamine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04803219 |
| 出典データセット | uspto-grants-1989_02 |
| ORD ID | ord-a211fe6f97894c4d861f90298e5ffa0a |
| 出典メモ | uspto-grants-1989_02 |