Hydrochloric Acid → HCID 14838488、化合物
反応式
C[O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[NH:9][C:10]1[CH:14]=[CH:13][N:12]([CH3:15])[N:11]=1.C(=O)(O)[O-].[Na+].[ClH:21]>ClCCl>[ClH:21].[CH3:15][N:12]1[CH:13]=[CH:14][C:10]([NH:9][C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=2[OH:2])=[N:11]1参加物
5
実験手順
The pyrazole from step (a) (1.7 g) was dissolved in dichloromethane (30 ml) under an atmosphere of nitrogen. Brown tribromide (8 ml) in dichloromethane was added dropwise and the mixture stirred at room temperature for 24 hours. After addition of dilute sodium bicarbonate, the organic phase was removed, dried and evaporated to give a pale oil, which was converted to the hydrochloride salt of the title compound, by trituration with ethereal HCl, to give an off-white solid, 0.75 g, mp 162°-164°.
後処理
- customthe organic phase was removed
- customdried
- customevaporated
- customto give a pale oil, which
出典と根拠
- ORDレコード
- ord-2fc4b1a7ce2645cfa82921faf02625ab
- 出典データセット
- uspto-grants-1989_02
- 特許番号
- US04803216
反応ノート
読み込み中…