化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Iodide → Hydrochloric Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Iodide | HCID 4875 | — |
| 反応物 | Sodium Carbonate | HCID 10340 | — |
| 反応物 | 1-(4-Fluorophenyl)piperazine | HCID 75260 | — |
| 反応物 | 4-Chloro-1-(4-chloro-3-methylphenoxy)-2-butanol | HCID 13323908 | — |
| 溶媒 | 1-Butanol | HCID 263 | — |
| 溶媒 | Isopropanol | HCID 3776 | — |
| 生成物 | Hydrochloric Acid | HCID 313 | — |
| 生成物 | HCID 14422854 | HCID 14422854 | — |
反応手順
This compound was prepared according to the procedure of Example 97. A mixture of 1.8 g (0.01 mole) of 1-(4-fluorophenyl)piperazine, 2.5 g (0.01 mole) of 4-chloro-1-(4-chloro-3-methylphenoxy)-2-butanol, 5.2 g (0.05 mole) of anhydrous sodium carbonate and 0.1 g of potassium iodide in a total volume of 200 ml of 1-butanol gave a golden oil as residue. The hydrochloride was formed in 2-propanol saturated with hydrogen chloride and the collected solid was recrystallized from methanol-water-ethyl ether to give 1.7 g (36%) of white solid, m.p. 199°-203° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04806555 |
| 出典データセット | uspto-grants-1989_02 |
| ORD ID | ord-bfbc08663b554189a380d68bbfdcde06 |
| 出典メモ | uspto-grants-1989_02 |