Dimethylamine → HCID 21274922、化合物
反応式
[CH3:1][NH:2][CH3:3].Br[CH2:5][CH2:6][O:7][C:8]1[CH:13]=[CH:12][C:11](/[C:14](/[C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)=[C:15](\[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)/[C:16]([F:19])([F:18])[F:17])=[CH:10][CH:9]=1>C(O)C>[CH3:1][N:2]([CH3:3])[CH2:5][CH2:6][O:7][C:8]1[CH:13]=[CH:12][C:11](/[C:14](/[C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)=[C:15](\[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)/[C:16]([F:19])([F:18])[F:17])=[CH:10][CH:9]=1参加物
4
実験手順
10 ml of a 40% aqueous solution of dimethylamine are added to a solution of 5.37 g (12 mmoles) of (E)-1-[4-(2-bromoethoxy)-phenyl]-1,2-diphenyl-3,3,3-trifluoro-propene, prepared as described in Example 7, in 10 ml of ethanol. The mixture is allowed to stand for 3-4 days, then evaporated, the residue is diluted with 50 ml of benzene, the resulting solution is washed with water until neutral, dried and evaporated. The residue is crystallized from hexane. 4.26 g (86.2%) of (E)-1-[4-(2-dimethylaminoethoxy)-phenyl]-1,2-diphenyl-3,3,3-trifluoro-propene are obtained; m.p.: 90°-91° C.